CANOS ORIGIN · NOW AVAILABLE
Cancer detection.
A deeper health baseline.
Canos Origin detects cancer signals in blood and brings together genetics, epigenetics and cfDNA to build your dog’s comprehensive genomic health baseline. Know more today. Bank their baseline for tomorrow.
Blood draws are open. We’re now processing samples.
THEIR OWN STARTING POINT
Because every dog’s normal is different.
- BLOOD DRAWS
- Open · Samples now processing
- WHO IT’S FOR
- Healthy dogs · 1 year+ · 5 kg+
- RESULTS
- About 1–2 weeks after your appointment
WHAT YOUR DOG GETS
One sample.
A fuller picture of their health.
EPIGENETICS + cfDNA
Cancer signals, detected.
Cancer detection
Origin reads cancer-associated patterns in cell-free DNA. Cancer detection is part of your dog’s health baseline, from the first blood draw.
cfDNA methylation profile
A genome-wide record of your dog’s methylation pattern and cfDNA signals, including cancer-associated patterns, banked for future comparisons.
Immune cell profile
Information about immune cell makeup and immune aging.
GENETIC HEALTH
346
Inherited diseases
Including carrier status
31
Physical traits
Coat, colour, size and shape
7
Drug responses
Including anaesthesia risk
321
Breeds
Ancestry, inbreeding and lineage
BIOLOGICAL AGE + EPIGENETIC MARKERS
Understand their aging alongside their genetics and cancer signals, from the same blood sample.
- Biological age
- Epigenetic markers
- Health baseline
THEIR OWN STARTING POINT
Keep a reference that belongs to them.
Their health today is a reference you can carry forward. Banking a genomic health baseline preserves the detail that makes your dog’s molecular profile their own.
Origin records inherited genetics, epigenetic patterns and cell-free DNA signals together. That makes future comparisons personal: a view of change against their own starting point.
01
Understand
Explore inherited health, traits and individual information.
02
Detect
Detect cancer signals through epigenetic and cfDNA analysis.
03
Bank
Save their genomic health baseline for future reference.
THREE WAYS TO GIVE BLOOD
A small draw.
A choice that fits your life.
A vet collects about 5 mL of blood. Every sample is processed in our San Carlos, California lab.
01
Group draw day
Canos Preventative Care Day · Saturday, 14 November 2026 · 10:00 am–3:00 pm, San Francisco time (PST) · Outside 490 Avenue of the Palms, Treasure Island, San Francisco.
No appointment needed
02
Mobile vet at home
A vet comes to your door in the Bay Area.
Schedule an appointment
03
My own vet
We ship a collection kit anywhere in the US.
Collection with your vet
For healthy dogs aged 1 year or older and weighing at least 5 kg (11 lb). If your dog is unwell, anaemic, or has recently had surgery or given blood, wait and speak with your vet first.
CANOS ORIGIN
Start with what makes them, them.
- Genetics, epigenetics and cfDNA analysis
- Cancer detection from blood
- A genomic health baseline, banked
- Biological age, traits and ancestry
Regular price $699Offer price $499
Cancer screening and a comprehensive genomic health baseline.(vet visit fee included)
Order online and choose your blood draw preference.
Order nowBlood draws are open. We’re now processing samples.
Does Origin include cancer detection?
Yes. Origin detects cancer-associated signals in cell-free DNA from a blood sample. It combines cancer detection with genetics and epigenetics to give you a comprehensive genomic health baseline to share with your vet.
How do I order Origin?
Choose Origin in the order form and select your blood draw preference: a mobile vet, your own vet or our group draw day. You can also book a free consultation with our team.
What are cfDNA and an epigenetic baseline?
Epigenetic marks help control how cells use DNA without changing its sequence. One type is DNA methylation. Tiny DNA fragments in the blood, called cell-free DNA (cfDNA), carry these marks. Origin records that pattern while your dog is healthy as a personal reference: their epigenetic baseline.
Why bank a baseline now?
Your dog’s molecular profile is personal. Recording it while they are healthy preserves a reference for future comparisons. Origin detects cancer signals alongside its genetic and epigenetic analysis, bringing cancer detection and a deeper view of their health into the same test.
How does Origin differ from Guardian?
Origin combines cancer screening with genetics, traits, ancestry, biological age and a comprehensive genomic health baseline. Guardian offers the cancer screening part of Origin as a focused $199 test. Both include cell-free DNA analysis and are available to order.
What is in the report?
Cancer screening and active cancer signals, cell-free DNA analysis, biological age, epigenetic markers and an immune cell profile. The genetic panel covers 346 inherited diseases, 31 physical traits, 7 drug responses and ancestry across 321 breeds, including inbreeding and lineage. Together, these form your dog’s comprehensive genomic health baseline.
What should I do with genetic results?
Share your results with your vet. Confirm important findings before making medical, medication or breeding decisions.
Who is Canos?
Canos is a veterinary diagnostics company founded by scientists from the University of Oxford and backed by Y Combinator (F26). We are based in San Francisco, with samples processed in our San Carlos, California lab. Our research collaborators include scientists from the Royal Veterinary College.
Who is Origin for?
Healthy dogs aged 1 year or older and weighing at least 5 kg (11 lb). Dogs that are unwell, anaemic, or have recently had surgery or given blood should wait. Smaller dogs will be added later. Your vet can help confirm whether now is a suitable time for a draw.
How is the blood collected?
A vet takes about 5 mL of blood. Choose our group draw day in San Francisco, a mobile vet visit at home in the Bay Area, or your own vet anywhere in the US with our collection kit. Samples are sent to our San Carlos lab.
When will I get results?
Results arrive about 1–2 weeks after your appointment. Our team reviews the report with your vet.
How much does it cost?
Origin is now $499, reduced from $699, with the vet visit fee included. This covers genetics, traits, ancestry, biological age, epigenetic markers, cell-free DNA analysis and cancer screening, brought together in a comprehensive genomic health baseline.
What happens to my dog’s data?
Data is de-identified and used for research only with your consent. You can withdraw and ask us to delete it at any time by emailing hello@canos.ai. We never share results with insurers for underwriting.
What does the research say?
Human and canine research has detected cancer-associated patterns in cfDNA. Methylation helps identify where DNA came from, while longitudinal studies show the value of tracking an individual’s molecular profile over time.
- Annals of Oncology, 2021: a targeted methylation blood test evaluated cancer signals across more than 50 human cancer types.
- Journal of Clinical Oncology, 2015: serial CA-125 measurements detected more ovarian cancers than a single threshold in a human screening study.
- Genome Medicine, 2026: longitudinal cfDNA profiles in healthy people showed stability within individuals.
- Nature Communications, 2018: tissue-specific methylation patterns helped identify the origins of human cfDNA.
Our 22 September 2026 preprint (version 1) analysed 896 plasma sequencing runs from 341 dogs across four studies. In the diagnostic subset, nested cross-validation achieved 90.6% sensitivity at 95.1% specificity. Our bioinformatics research compares and integrates complementary cfDNA signals across canine cancer studies. Read the Canos research preprint.
THE SCIENCE BEHIND ORIGIN
Developed by scientists from the University of Oxford. In collaboration with scientists from the Royal Veterinary College. Backed by Y Combinator.
NANOPORE SEQUENCING · NATIVE METHYLATION
FRAGMENTOMICS · AI PATTERN ANALYSIS
Samples processed in San Carlos, California.
Pet parent guides
Understand your dog’s test.
Understanding blood tests
Can blood tests detect cancer in dogs?
Understand routine bloodwork, liquid biopsy and the questions to ask before choosing a cancer-related test for your dog.
Read guideChoosing the right test
Dog genetic testing versus cancer testing: what’s the difference?
Explore how Canos Origin brings cancer detection, genetics, epigenetics and cfDNA together in a comprehensive genomic health baseline.
Read guide